Search results for "Hepatic carcinoma"

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Does low concentration mycotoxin exposure induce toxicity in HepG2 cells through oxidative stress?

2020

The purpose of this study was to determine whether exposure to low concentrations of deoxynivalenol (DON), T-2 toxin (T-2) and patulin (PAT) in a human hepatocellular carcinoma cell line (HepG2) exerts toxic effects through mechanisms related to oxidative stress, and how cells deal with such exposure. Cell viability was determined by the MTT and protein content (PC) assays over 24, 48 and 72 h. The IC

Time FactorsCell SurvivalHealth Toxicology and MutagenesisMitochondria LiverHepatic carcinoma010501 environmental sciencesToxicologymedicine.disease_cause01 natural sciencesPatulinInhibitory Concentration 5003 medical and health scienceschemistry.chemical_compoundmedicineHumansMycotoxinVolume concentration0105 earth and related environmental sciencesMembrane Potential Mitochondrial0303 health sciencesDose-Response Relationship DrugToxinChemistry030302 biochemistry & molecular biologyfood and beveragesHep G2 CellsMycotoxinsMolecular biologydigestive system diseasesOxidative StressT-2 ToxinPatulinHepg2 cellsToxicityHepatocytesLipid PeroxidationReactive Oxygen SpeciesTrichothecenesOxidative stressToxicology Mechanisms and Methods
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